The role of central reading centers – current practices and future directions
نویسندگان
چکیده
Central reading centers (CRCs) have several crucial roles in the conduct of clinical trials, providing key input during the study design, preparation of the operations manual, as well as site and photographer certification. They provide objective, standardized grading of images from study subjects, which determines study eligibility, and also evaluate lesion features at subsequent study visits. CRCs need to adhere strictly to Good Clinical Practice (GCP) guidelines, as well as the established standard operating procedures in order to ensure that images are graded properly. The role of CRCs will continue to evolve, and include the use of web-based image transmission and grading platforms.
منابع مشابه
Differences in Reading Beliefs/Practices of L2 Teachers: Undergraduate versus Graduate Degree Holders
In their attempt to shed light on the factors contributing to the incongruity between L2 reading teachers’ beliefs and practices, most of the researchers have resorted to teachers’ personal perspectives. As a partial replication of the research carried out by Karimi and Dehghani (2016), the current study sought to broaden this restricted scope by examining the role of te...
متن کاملMotivation to Read in a Second Language: A Review of Literature
Reading motivation is a well-researched topic in relation to first language literacy development due to its influence on both reading processes and outcomes. In second language reading, the role of motivation has not been as thoroughly explored. The aim of this review of literature is to highlight established studies as well as recent explorations in some recurring areas of first and second lan...
متن کاملFuture Directions for the Organizational Readiness for Knowledge Translation (OR4KT) Tool: Response to Recent Commentaries
متن کامل
Patient Engagement and its Evaluation Tools – Current Challenges and Future Directions; Comment on “Metrics and Evaluation Tools for Patient Engagement in Healthcare Organization- and System-Level Decision-Making: A Systematic Review”
Considering the growing recognition of the importance of patient engagement in healthcare decisions, research and delivery systems, it is important to ensure high quality and efficient patient engagement evaluation tools. In this commentary, we will first highlight the definition and importance of patient engagement. Then we discuss the psychometric properties of the patient engagement evaluati...
متن کاملThe Role of ZPD in Estimating Learners’ Future Level of Development: The Case of Reading Ability
The present study aimed at investigating the possible impact ofZone of Proximal Development (ZPD) on the learners’ performance. Forty-sixIranian university students participated in this study by taking two types of readingcomprehension tests (i.e., the main idea and Wh-question type). The researchersused the Winstep program to analyze the data and estimate the learners’ Raschmeasure in pre, pos...
متن کامل